Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
GPT2 / ALT2 is a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Gene Name: | glutamic pyruvate transaminase (alanine aminotransferase) 2 |
Synonyms: | GPT2, Alanine aminotransferase 2, AAT2, ALT2, GPT 2 |
Target Sequences: | Q8TD30 Q8TD30 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.