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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
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GPRASP1 / GASP-1
G protein-coupled receptor associated sorting protein 1
GPRASP1 / GASP-1 is a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified.
| Gene Name: | G protein-coupled receptor associated sorting protein 1 |
| Synonyms: | GPRASP1, GASP1, KIAA0443, GASP-1, GASP |
| Target Sequences: | AB007903 BAA23715.3 Q5JY77 |
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