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Zn2+ acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.
Gene Name: | G protein-coupled receptor 39 |
Family/Subfamily: | GPCR , Orphan-A |
Synonyms: | GPR39, G protein-coupled receptor 39, G-protein coupled receptor 39 |
Target Sequences: | NM_001508 NP_001499.1 O43194 |
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