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GPR183 / EBI2

G protein-coupled receptor 183

Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals constitutively also via MAPK1/3 (ERK1/2).

Gene Name: G protein-coupled receptor 183
Family/Subfamily: GPCR , Orphan-A
Synonyms: GPR183, EBI 2, EBI2, EBV-induced gene 2, G protein-coupled receptor 183, G-protein coupled receptor 183
Target Sequences: NM_004951 NP_004942.1 P32249

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
GPR183 / EBI2 (4)
No (4)
ABP-His, N-terminus (1)
GST (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
GPR183 / EBI2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41 kDa
100 µg/$494
GPR183 / EBI2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
41 kDa
20 µg/$150
GPR183 / EBI2 Protein
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E. coli
ABP-His, N-terminus
18.2 kDa
50 µg/$419
GPR183 / EBI2 Protein - 12.5% SDS-PAGE of human EBI2 stained with Coomassie Blue
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Wheat Germ Extract
GST
65.45 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).