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Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.
Gene Name: | glycosylphosphatidylinositol anchor attachment 1 |
Synonyms: | GPAA1, GAA1 protein homolog, GPI transamidase subunit, GAA1, HGAA1 |
Target Sequences: | NM_003801 NP_003792.1 O43292 |
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