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Goat IgG

Representing approximately 75% of serum antibodies, IgG is the most common type of antibody found in the circulation. IgG molecules are created and released by plasma B cells. IgG antibodies are large molecules of about 150 kDa made of four peptide chains. It contains two identical class gamma heavy chains of about 50 kDa and two identical light chains of about 25 kDa. The two heavy chains are linked to each other and to a light chain each by disulfide bonds. The resulting tetramer has two identical halves, which together form the Y-like shape. Each end of the fork contains an identical antigen binding site. The Fc regions of IgGs bear a highly conserved N-glycosylation site.

Goat IgG Target Details

Target Name: Goat IgG

Publications (3)

1
Critical role for white blood cell NAD(P)H oxidase-mediated plasminogen activator inhibitor-1 oxidation and ventricular rupture following acute myocardial infarction. Agarwal U, Zhou X, Weber K, Dadabayev AR, Penn MS. Journal of molecular and cellular cardiology. 2011 50:426-32. (IHC; Goat) [PubMed:20807543]
2
Long non-coding RNA LINC00968 reduces cell proliferation and migration and angiogenesis in breast cancer through up-regulation of PROX1 by reducing hsa-miR-423-5p. Xianfu Sun, Tao Huang, Chengjuan Zhang, Shengze Zhang, Yingjie Wang, Qiang Zhang, Zhenzhen Liu. Cell cycle (Georgetown, Tex.). 2019 Aug;18:1908-1924. [Full Text Article] [PubMed:31213129] [PMC:PMC6681781]
3
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2. Jim Baggen, Leentje Persoons #, Els Vanstreels #, Sander Jansen #, Dominique Van Looveren , Bram Boeckx , Vincent Geudens, Julie De Man, Dirk Jochmans, Joost Wauters, Els Wauters, Bart M Vanaudenaerde, Diether Lambrechts , Johan Neyts, Kai Dallmeier, Hendrik Jan Thibaut , Maarten Jacquemyn, Piet Maes, Dirk Daelemans. The Breast : official journal of the European Society of Mastology. 2021 Apr;;53:435-444. [Full Text Article] [PubMed:33686287] Related Antibodies: LS-C752241.

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0.146 - 37.5 µg/ml
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).