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Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).
Gene Name: | Guanine Nucleotide Binding Protein (G Protein), Gamma Transducing Activity Polypeptide 1 |
Synonyms: | GNGT1, Transducin gamma chain, GNG1 |
Target Sequences: | NM_021955 NP_068774.1 P63211 |
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