GNB3

guanine nucleotide binding protein (G protein), beta polypeptide 3

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

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Products

Antibodies (14)

Type

Primary (14)

Target

GNB3 (14)

Reactivity

Human (12)

Mouse (5)

Rat (5)

Bat (1)

Bovine (1)

Chicken (1)

Chimpanzee (3)

Dog (1)

Gibbon (3)

Horse (1)

Monkey (5)

Pig (1)

Rabbit (1)

Xenopus (2)

Zebrafish (1)

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Application

IHC (2)

IHC-P (1)

WB (14)

ELISA (4)

IF (3)

Peptide-ELISA (3)

Host

rabbit (11)

mouse (1)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (5)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (13)

Clone

M1-1-1D5 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (11)

Epitope

aa268-317 (4)

aa186-197 (1)

aa309-321 (1)

Publications

No (13)

Yes (1)

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IHC-plus™ GNB3 Antibody (aa309-321) LS-B8347

(5.0) Rating

(1) Publication(s)

Antibody:

GNB3 Goat anti-Human Polyclonal (aa309-321) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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GNB3 Antibody (aa186-197) LS-C54921

Antibody:

GNB3 Goat anti-Human Polyclonal (aa186-197) Antibody

Reactivity:

Xenopus, Zebrafish, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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GNB3 Antibody (clone M1-1-1D5) LS-C197318

Antibody:

GNB3 Mouse anti-Human Monoclonal (M1-1-1D5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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GNB3 Antibody LS-C665908

Antibody:

GNB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$331

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GNB3 Antibody LS-C665906

Antibody:

GNB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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GNB3 Antibody LS-C808002

Antibody:

GNB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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GNB3 Antibody LS-C778503

Antibody:

GNB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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GNB3 Antibody LS-C766913

Antibody:

GNB3 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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GNB3 Antibody LS-C331439

Antibody:

GNB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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GNB3 Antibody (aa268-317) LS-C205832

Antibody:

GNB3 Rabbit anti-Human Polyclonal (aa268-317) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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GNB3 Antibody (aa268-317, HRP) LS-C468554

Antibody:

GNB3 Rabbit anti-Human Polyclonal (aa268-317) (HRP) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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GNB3 Antibody (aa268-317, Biotin) LS-C468552

Antibody:

GNB3 Rabbit anti-Human Polyclonal (aa268-317) (Biotin) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

GNB3 Antibody (aa268-317, FITC) LS-C468553

Antibody:

GNB3 Rabbit anti-Human Polyclonal (aa268-317) (FITC) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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GNB3 Antibody LS-C667826

Antibody:

GNB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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