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GLUL / Glutamine Synthetase
glutamate-ammonia ligase
GLUL / Glutamine Synthetase belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
| Gene Name: | glutamate-ammonia ligase |
| Synonyms: | GLUL, GLNS, Glutamate decarboxylase, Glutamate-ammonia ligase, Glutamine synthase, GS, Glutamate--ammonia ligase, Glutamine synthetase, PIG43, PIG59 |
| Target Sequences: | NM_002065 NP_002056.2 P15104 |
Publications (3)
1
GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism. Magesh Muthu, Ranjeet Kumar, Azharuddin Sajid Syed Khaja, Jonathan D Gilthorpe, Jenny L Persson, Anders Nordström. Cancers. 2019 Dec;11:1945. [Full Text Article]
[PubMed:31817360]
[PMC:PMC6966511]
Related Antibodies: LS-C114787.
2
Toll-Like Receptor 9-Mediated Neuronal Innate Immune Reaction Is Associated with Initiating a Pro-Regenerative State in Neurons of the Dorsal Root Ganglia Non-Associated with Sciatic Nerve Lesion. Petr Dubový, Ivana Hradilová-Svíženská, Václav Brázda, Marek Joukal. International journal of molecular sciences. 2021 July;22:7446. [Full Text Article]
[PubMed:34299065]
[PMC:PMC8304752]
Related Antibodies: LS-B2579.
3
Bilateral elevation of interleukin-6 protein and mRNA in both lumbar and cervical dorsal root ganglia following unilateral chronic compression injury of the sciatic nerve. Dubov[Character fd] P, Br[Character e1]zda V, Klus[Character e1]kov[Character e1] I, Hradilov[Character e1]-Sv[Character ed]ensk[Character e1] I. Journal of neuroinflammation. 2013 10:55. [Full Text Article]
[PubMed:23634725]
[PMC:PMC3657546]
Related Antibodies: LS-B2579.
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Antibodies
(81)
Type
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(81)
Target
GLUL / Glutamine Synthetase
(81)
Reactivity
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(53)
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(25)
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(7)
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(3)
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(4)
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(3)
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(3)
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(3)
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(4)
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(4)
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(3)
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(1)
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(3)
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(4)
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(18)
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(70)
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(33)
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(9)
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(7)
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(9)
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Publications
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(79)
Yes
(2)
Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Mouse anti-Sheep Monoclonal (GS-6) Antibody
Sheep, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$545
GLUL / Glutamine Synthetase Rabbit anti-Rat Polyclonal Antibody
Mouse, Bovine, Rat, Human
IF, IHC, IHC-P, IHC-Pfa, WB
Unconjugated
0.1 ml/$460
GLUL / Glutamine Synthetase Mouse anti-Human Monoclonal (OTI1F4) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
GLUL / Glutamine Synthetase Mouse anti-Human Monoclonal (Carrier-free) (OTI1F4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Mouse anti-Human Monoclonal (AT8D7) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$460
Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa301-350) (HRP) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa301-350) (Biotin) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa301-350) (FITC) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
Cancer Pathology
Cancer
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
GLUL / Glutamine Synthetase Rabbit anti-Bovine Polyclonal Antibody
Mouse, Bovine, Rat
IHC, WB
Unconjugated
100 µl/$649
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$341
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$287; 100 µl/$431
Cancer Pathology
Fast Shipping
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
Cancer Pathology
Fast Shipping
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa70-96) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$391; 100 µl/$489
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa70-96) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa70-96) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
GLUL / Glutamine Synthetase Rabbit anti-Human Polyclonal (aa70-96) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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