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Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Gene Name: | glutaminase 2 (liver, mitochondrial) |
Synonyms: | GLS2, GA, Glutaminase 2, Glutaminase I, Glutaminase GA, L-glutaminase, HLGA, L-glutamine amidohydrolase, LGA, Breast cell glutaminase |
Target Sequences: | NM_013267 NP_037399.2 Q9UI32 |
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