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Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Crucial regulator of cellular iron homeostasis and hemoglobin maturation. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Gene Name: | glutaredoxin 3 |
Synonyms: | GLRX3, BA500G10.4, Glutaredoxin-3, GRX3, GLRX4, Glutaredoxin 4, PICOT, Thioredoxin-like protein 2, Thioredoxin-like, Thioredoxin-like 2, TXNL2, TXNL3, Glutaredoxin 3, GRX4, PKC-theta-interacting protein, PKCq-interacting protein |
Target Sequences: | NM_006541 NP_006532.2 O76003 |
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