GLRX2 / Glutaredoxin 2

glutaredoxin 2

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

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Products

ELISA Kits (6)

Type

Custom (2)

Sandwich (4)

Target

GLRX2 / Glutaredoxin 2 (6)

Reactivity

Human (2)

Mouse (1)

Rat (2)

Bovine (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (4)

Publications

No (6)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (2)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

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Human GLRX2 / Glutaredoxin 2 (Sandwich ELISA) ELISA Kit - LS-F66839

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse GLRX2 / Glutaredoxin 2 (Sandwich ELISA) ELISA Kit - LS-F66935

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Bovine GLRX2 / Glutaredoxin 2 (Custom) ELISA Kit - LS-F65212

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$669

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Rat GLRX2 / Glutaredoxin 2 (Custom) ELISA Kit - LS-F65921

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$669

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Rat GLRX2 / Glutaredoxin 2 (Sandwich ELISA) ELISA Kit - LS-F74134

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

Select

Human GLRX2 / Glutaredoxin 2 (Sandwich ELISA) ELISA Kit - LS-F74342

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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