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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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GLP2R
glucagon-like peptide 2 receptor
GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition.
Glucagon-like peptide-2 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro. Baldassano S, Liu S, Qu MH, Mul F, Wood JD. American journal of physiology. Gastrointestinal and liver physiology. 2009 297:G800-5. (IHC; Guinea pig)[Full Text Article]
[PubMed:19628655]
[PMC:PMC2763802]
Related Antibodies: LS-A1312.
3
Influence of Cane Molasses Inclusion to Dairy Cow Diets during the Transition Period on Rumen Epithelial Development. William F Miller, Evan C Titgemeyer, Tiruvoor G Nagaraja, Daniel H M Watanabe, Luana D Felizari, Danilo D Millen, Zachary K Smith, Bradley J Johnson. Animals: an open access journal from MDPI. 2021 April;11: [Full Text Article]
[PubMed:33923260]
[PMC:PMC8145355]
Related Antibodies: LS-A1312.
4
GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk. Wei He, Osmond D Rebello, Antonia Henne, Fabian Nikolka, Thomas Klein, Kathrin Maedler. Frontiers in endocrinology. 2021 July;12:697120. [Full Text Article]
[PubMed:34290670]
[PMC:PMC8287580]
Related Antibodies: LS-A1312.
5
Acute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome. Thymann T, Stoll B, Mecklenburg L, Burrin DG, Vegge A, Qvist N, Eriksen T, Jeppesen PB, Sangild PT. Journal of pediatric gastroenterology and nutrition. 2014 Jun;58:694-702. [Full Text Article]
[PubMed:24399211]
Related Antibodies: LS-A1312.
6
Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration. El-Jamal N, Erdual E, Neunlist M, Koriche D, Dubuquoy C, Maggiotto F, Chevalier J, Berrebi D, Dubuquoy L, Boulanger E, Cortot A, Desreumaux P. American journal of physiology. Gastrointestinal and liver physiology. Aug;307:G274-85. [Full Text Article]
[PubMed:24875097]
Related Antibodies: LS-A1312.
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PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).