GLIS2

GLIS family zinc finger 2

GLIS2 is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

GLIS2 (4)

Publications

No (4)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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GLIS2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108726

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.5 kDa

Price:

100 µg/$710

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Human GLIS2 Protein (Recombinant His, N-Terminal) - LS-G144981

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

55.5 kDa

Price:

50 µg/$419

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Human GLIS2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92245

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.5 kDa

Price:

20 µg/$215

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Human GLIS2 Protein (Recombinant GST) (Full Length) - LS-G35794

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.59 kDa

Price:

2 µg/$439

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