order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
GLIS2
GLIS family zinc finger 2
GLIS2 is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.
| Gene Name: | GLIS family zinc finger 2 |
| Synonyms: | GLIS2, GLI-similar 2, GLI-similar protein 2, GLIS family zinc finger 2, Nephrocystin-7, Neuronal Krueppel-like protein, NKL, NPHP7, Zinc finger protein GLIS2 |
| Target Sequences: | NM_032575 NP_115964.2 Q9BZE0 |
Publications (1)
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
