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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600


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GLI3

GLI family zinc finger 3

Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in regulating the size of the zone of distal chondrocytes, in restricting the zone of PTHLH expression in distal cells and in activating chondrocyte proliferation. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

Gene Name: GLI family zinc finger 3
Synonyms: GLI3, ACLS, GCPS, GLI-Kruppel family member GLI3, GLI3 full length protein, GLI3-190, GLI family zinc finger 3, Gli-3, GLI3FL, PAP-A, PAPA1, PHS, PPDIV, Transcriptional activator GLI3, PAPA, PAPB, GLI3 form of 190 kDa, Oncogene GLI3, Zinc finger protein GLI3
Target Sequences: NM_000168 NP_000159.3 P10071

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Products
Antibodies (25)
Primary (25)
GLI3 (25)
Human (17)
Mouse (13)
Rat (5)
Bat (1)
Bovine (1)
Chicken (3)
Chimpanzee (1)
Dog (2)
Hamster (1)
Horse (1)
Monkey (1)
Pig (1)
Quail (1)
Rabbit (2)
Squirrel monkey (1)
Xenopus (1)
Xenopus laevis (1)
IHC (5)
IHC-P (2)
WB (21)
Flo (1)
ELISA (6)
ICC (1)
IF (6)
IP (1)
Peptide-ELISA (2)
rabbit (22)
mouse (1)
goat (2)
Product Group
IHCPlus (1)
IgG (6)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (24)
2C9 (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (2)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (11)
aa111-343 (8)
aa303-561 (8)
30-110 aa, N-terminal (1)
aa11-60 (1)
aa40-57 (1)
aa431-442 (1)
No (25)
GLI3 Antibody - Anti-GLI3 antibody IHC of human brain-glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml.
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GLI3 Rabbit anti-Human Polyclonal Antibody
Xenopus laevis, Quail, Chicken, Dog, Human, Chimpanzee, Squirrel monkey
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$515
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Mouse Polyclonal (aa303-561) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
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GLI3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
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GLI3 Goat anti-Human Polyclonal (aa431-442) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Pig, Horse, Bat, Human
Peptide-ELISA
Unconjugated
100 µg/$401
GLI3 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GLI-3 Antibody. The picture on the right is blocked with the synthesized peptide.
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GLI3 Rabbit anti-Human Polyclonal (aa11-60) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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GLI3 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GLI3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GLI-3 antibody.
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GLI3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
GLI3 Antibody - Immunofluorescence of monoclonal antibody to GLI3 on HeLa cell . [antibody concentration 10 ug/ml]
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GLI3 Mouse anti-Human Monoclonal (2C9) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
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GLI3 Goat anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, WB
Unconjugated
100 µg/$962
GLI3 Antibody - WB of GLI3 antibody. All lanes: Anti-GLI3 at 0.5ug/ml. Lane 1: Rat Testis Tissue Lysate at 40ug. Lane 2: A549 Whole Cell Lysate at 40ug. Lane 3: SW620 Whole Cell Lysate at 40ug. Predicted bind size: 170KD. Observed bind size: 80KD.
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GLI3 Rabbit anti-Human Polyclonal (aa40-57) Antibody
Xenopus, Chicken, Rabbit, Rat, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLI3 Rabbit anti-Human Polyclonal (aa111-343) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
GLI3 Antibody - Western blot of recombinant GLI3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLI3 Rabbit anti-Human Polyclonal (aa111-343) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Viewing 1-25 of 25 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).