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GLI / GLI1
GLI family zinc finger 1
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
| Gene Name: | GLI family zinc finger 1 |
| Synonyms: | GLI1, Gli-1, GLI family zinc finger 1, Glioma-associated oncogene, Glioma-associated oncogene 1, Oncogene GLI, GLI, Zinc finger protein GLI1 |
| Target Sequences: | NM_005269 NP_005260.1 P08151 |
Publications (6)
1
Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Niemann C, Unden AB, Lyle S, Zouboulis ChC, Toftgrd R, Watt FM. Proceedings of the National Academy of Sciences of the United States of America. 2003 11873-80.
[PubMed:12917489]
[PMC:PMC304101]
2
Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. Qualtrough D, Buda A, Gaffield W, Williams AC, Paraskeva C. International journal of cancer. Journal international du cancer. 2004 110:831-7.
[PubMed:15170664]
3
Hedgehog signaling drives cellular survival in human colon carcinoma cells. Mazumdar T, DeVecchio J, Shi T, Jones J, Agyeman A, Houghton JA. Cancer research. 2011 71:1092-102. (WB; Human)
[PubMed:21135115]
[PMC:PMC3032813]
☰ Filters
Products
Proteins
(8)
Type
Over-Expression Lysate
(2)
Recombinant
(6)
Target
GLI / GLI1
(8)
Publications
No
(8)
Tag
6His, N-terminus
(1)
GST, N-terminus
(2)
His
(1)
His-T7
(1)
Myc-DDK (Flag)
(3)
Species
Human
(6)
Rat
(1)
Source
293T Cells
(1)
E. coli
(3)
HEK 293 Cells
(2)
Wheat Germ Extract
(2)
Low Endotoxin Level
Low endotoxin level
(1)
E. coli
6His, N-terminus
23.3 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
117.7 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
117.7 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
117.7 kDa
20 µg/$150
E. coli
115 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.76 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
E. coli
His-T7
35.0 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
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