Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Gene Name: | glycine dehydrogenase (decarboxylating) |
Synonyms: | GLDC, GCSP, Glycine decarboxylase, HYGN1, GCE, Glycine dehydrogenase, NKH |
Target Sequences: | NM_000170 NP_000161.2 P23378 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.