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Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
Gene Name: | glucuronic acid epimerase |
Synonyms: | GLCE, D-glucuronyl C5-epimerase, Glucuronyl C5-epimerase, Heparan sulfate C5-epimerase, Heparan sulfate epimerase, HSEPI, KIAA0836, UDP-glucuronic acid epimerase, Glucuronic acid epimerase |
Target Sequences: | AB020643 BAA74859.1 O94923 |
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