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GGT1 / GGT
gamma-glutamyltransferase 1
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
| Gene Name: | gamma-glutamyltransferase 1 |
| Family/Subfamily: | Protease , Threonine T3 |
| Synonyms: | GGT1, CD224 antigen, CD224, Ec 2.3.2.2, Glutamyl transpeptidase, GTG, Gamma-glutamyltransferase, Glutathione hydrolase 1, GLUTATHIONURIA, Gamma-glutamyl transpeptidase, Gamma-glutamyltransferase 1, Gamma-glutamyltranspeptidase 1, GGT, Leukotriene-C4 hydrolase, D22S672, D22S732, Gamma-glutamyltransferase 2, GGT 1 |
| Target Sequences: | NM_005265 AAH25927.1 P19440 |
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Antibodies
(67)
Type
Primary
(67)
Target
GGT1 / GGT
(67)
Reactivity
Human
(57)
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(32)
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(11)
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(2)
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(6)
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(12)
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(1)
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(7)
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(59)
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(1)
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(25)
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(3)
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(2)
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(3)
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(54)
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(11)
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(2)
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(4)
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(28)
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(1)
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(8)
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(1)
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monoclonal mc
(10)
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(57)
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(3)
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(6)
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(2)
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(7)
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(3)
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(3)
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(7)
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(7)
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(6)
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(28)
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aa122-299
(9)
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(8)
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(7)
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(7)
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(2)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
aa370-569
(1)
Publications
No
(67)
GGT1 / GGT Mouse anti-Human Monoclonal (1F9) Antibody
Mouse, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
GGT1 / GGT Rabbit anti-Human Polyclonal (aa1-226) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
GGT1 / GGT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
GGT1 / GGT Rabbit anti-Rat Polyclonal (aa12-39) Antibody
Mouse, Rat
WB
Unconjugated
400 µl/$393
GGT1 / GGT Mouse anti-Human Monoclonal (138H11) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
500 µl/$967
GGT1 / GGT Goat anti-Human Polyclonal (aa27-40) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
GGT1 / GGT Goat anti-Human Polyclonal (aa180-193) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
GGT1 / GGT Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
GGT1 / GGT Rabbit anti-Human Polyclonal (aa124-152) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
GGT1 / GGT Rabbit anti-Human Polyclonal (aa122-299) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511
GGT1 / GGT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
GGT1 / GGT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GGT1 / GGT Rabbit anti-Human Polyclonal (aa1-225) Antibody
Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GGT1 / GGT Rabbit anti-Mouse Polyclonal Antibody
Mouse
IHC, IHC-P
Unconjugated
100 µl/$412
GGT1 / GGT Rabbit anti-Mouse Polyclonal (aa12-39) Antibody
Rabbit, Mouse
ELISA, WB
Unconjugated
200 µl/$734
GGT1 / GGT Rabbit anti-Mouse Polyclonal (aa12-39) (Biotin) Antibody
Rabbit, Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
GGT1 / GGT Rabbit anti-Mouse Polyclonal (aa12-39) (FITC) Antibody
Rabbit, Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
GGT1 / GGT Rabbit anti-Mouse Polyclonal (aa12-39) (APC) Antibody
Rabbit, Mouse
ELISA, WB
APC Conjugated
200 µl/$952
GGT1 / GGT Rabbit anti-Mouse Polyclonal (aa12-39) (Azide-free) (HRP) Antibody
Rabbit, Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
GGT1 / GGT Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
GGT1 / GGT Rabbit anti-Human Polyclonal (aa1-569) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$749
GGT1 / GGT Rabbit anti-Human Polyclonal (aa124-152) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
GGT1 / GGT Rabbit anti-Human Polyclonal (11-60 aa, N-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GGT1 / GGT Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
GGT1 / GGT Rabbit anti-Human Polyclonal (aa21-70) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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