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GFM2

G elongation factor, mitochondrial 2

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: G elongation factor, mitochondrial 2
Synonyms: GFM2, EFG2, HEFG2, MRRF2, MST027, MEF-G 2, MSTP027, RRF2, RRF2mt, EF-G2mt, Elongation factor G2
Target Sequences: NM_032380 NP_115756.2 Q969S9

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Products
Antibodies (14)
Primary (14)
GFM2 (14)
Human (14)
Mouse (2)
Rat (2)
Horse (3)
Monkey (3)
Pig (3)
IHC (4)
IHC-P (2)
WB (13)
ELISA (5)
ICC (1)
IF (5)
Peptide-ELISA (2)
rabbit (14)
IgG (9)
polyclonal pc (14)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (11)
aa435-484 (4)
410-490 aa, Internal (1)
Internal (1)
aa441-490 (1)
No (14)
GFM2 Antibody - Immunohistochemical analysis of GFM2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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GFM2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351
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GFM2 Rabbit anti-Human Polyclonal (410-490 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GFM2 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
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GFM2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GFM2 Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using GFM2 antibody.
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GFM2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$357
GFM2 Antibody - Immunofluorescence analysis of A549 cells, using GFM2 Antibody. The picture on the right is blocked with the synthesized peptide.
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GFM2 Rabbit anti-Human Polyclonal (aa441-490) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GFM2 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
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GFM2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
GFM2 Antibody - Staining LOVO cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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GFM2 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GFM2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
GFM2 Antibody - Sample (30 ug of whole cell lysate) A: HepG2 7.5% SDS PAGE GFM2 antibody diluted at 1:1000
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GFM2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
WB
Unconjugated
100 µl/$450
GFM2 Antibody - GFM2 antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GFM2 Rabbit anti-Human Polyclonal (aa435-484) Antibody
Human
WB
Unconjugated
100 µl/$424
GFM2 Antibody - GFM2 antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GFM2 Rabbit anti-Human Polyclonal (aa435-484) (HRP) Antibody
Pig, Horse, Human, Monkey
WB
HRP Conjugated
100 µl/$469
GFM2 Antibody - GFM2 antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GFM2 Rabbit anti-Human Polyclonal (aa435-484) (Biotin) Antibody
Pig, Horse, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
GFM2 Antibody - GFM2 antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GFM2 Rabbit anti-Human Polyclonal (aa435-484) (FITC) Antibody
Pig, Horse, Human, Monkey
WB
FITC Conjugated
100 µl/$469
GFM2 Antibody - Western blot analysis of extracts of various cell lines, using GFM2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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GFM2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-14 of 14 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).