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GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
| Gene Name: | golgi to ER traffic protein 4 homolog (S. cerevisiae) |
| Synonyms: | GET4, C7orf20, CGI-20, Conserved edge protein, CEE, H_NH1244M04.5, TRC35 |
| Target Sequences: | NM_015949 NP_057033.2 Q7L5D6 |
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