GDNF

glial cell derived neurotrophic factor

GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.

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Products

Proteins (29)

Type

Over-Expression Lysate (8)

Recombinant (21)

Target

GDNF (29)

Format

Animal-free (3)

Publications

No (29)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (4)

His, N-Terminal (1)

His-SUMO (1)

Myc-DDK (Flag) (8)

Species

Human (17)

Mouse (4)

Rat (3)

Rhesus monkey (1)

Source

293T Cells (4)

CHO Cells (1)

E. coli (17)

HEK 293 Cells (4)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (10)

Low Endotoxin Level

Low endotoxin level (13)

Biologically Active

Biologically active (10)

Animal-free

Animal-free (3)

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Human GDNF Protein (Recombinant) - LS-G439

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15 kDa

Price:

2 µg/$268; 10 µg/$349

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Human GDNF Protein (Recombinant) - LS-G3632

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Mouse GDNF Protein (Recombinant) - LS-G471

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15.1 kDa-30.2 kDa

Price:

2 µg/$268; 10 µg/$349

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Mouse GDNF Protein (Recombinant) - LS-G3692

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Molecular Weight:

15.1 kDa-30.2 kDa

Price:

2 µg/$282; 10 µg/$370

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Rat GDNF Protein (Recombinant) - LS-G475

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15 kDa

Price:

2 µg/$268; 10 µg/$349

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Rat GDNF Protein (Recombinant) - LS-G3708

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$282; 10 µg/$370

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Human GDNF Protein (Recombinant) (aa78-211) - LS-G5831

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

30.1 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Human GDNF Protein (Recombinant) (Ser78-Ile211) - LS-G38758

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.1kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human GDNF Protein (Recombinant GST, N-terminus) (aa78-177) - LS-G58678

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102585

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.8 kDa

Price:

100 µg/$494

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GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102586

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.6 kDa

Price:

100 µg/$494

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Rhesus monkey GDNF Protein (Recombinant 6His, C-terminus) (Phe29-Ala258) - LS-G39446

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.6kD

Price:

10 µg/$266; 50 µg/$339; 500 µg/$1,010; 1 mg/$1,329

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Human GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76130

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.72 kDa

Price:

20 µg/$150

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Human GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76131

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.72 kDa

Price:

20 µg/$150

Select

Human GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76132

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.8 kDa

Price:

20 µg/$150

Select

Human GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76133

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.6 kDa

Price:

20 µg/$150

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Human GDNF Protein (Recombinant) (Ser78-Ile211) - LS-G145633

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

17 kDa

Price:

1 mg/$2,653; 10 µg/$296; 50 µg/$478

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GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123460

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.72 kDa

Price:

100 µg/$494

Select

GDNF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123140

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.72 kDa

Price:

100 µg/$494

Select

Human GDNF Protein (Recombinant) - LS-G131314

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~15 kDa

Price:

10 µg/$353

Select

Human GDNF Protein (Recombinant) (Ser78-Ile211) - LS-G140176

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.1 kDa

Price:

20 µg/$360; 100 µg/$728

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Human GDNF Protein (Recombinant His) (aa109-211) - LS-G140916

Source:

E. coli

Sequence Length:

102 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

11.33 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human GDNF Protein (Recombinant His-SUMO) (aa78-211) - LS-G20761

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

31.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse GDNF Protein (Recombinant) - LS-G27230

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

17-22 kDa (SDS-PAGE)

Price:

5 µg/$278; 25 µg/$381

Select

Human GDNF Protein (Recombinant GST) (Full Length) - LS-G28609

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.1 kDa

Price:

2 µg/$439

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