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Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Gene Name: | GDP dissociation inhibitor 1 |
Synonyms: | GDI1, 1A, GDP dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, Rab GDI alpha, OPHN2, RABGD1A, RABGDIA, XAP4, GDIL, MRX41, MRX48, XAP-4 |
Target Sequences: | NM_001493 NP_001484.1 P31150 |
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