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GDF9 / GDF-9

growth differentiation factor 9

Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Gene Name: growth differentiation factor 9
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: GDF9, GDF-9
Target Sequences: NM_005260 NP_005251.1 O60383

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
GDF9 / GDF-9 (8)
No (8)
GST (2)
His (1)
His, N-Terminal (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Human (5)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
GDF9 / GDF-9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
51.56 kDa
20 µg/$215
GDF9 / GDF-9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
51.56 kDa
100 µg/$710
GDF9 / GDF-9 Protein - Active Growth Differentiation Factor 9 (GDF9) by WB
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E. coli
His, N-Terminal
18kDa
10 µg/$342; 50 µg/$822; 200 µg/$1,457; 100 µg/$1,239; 1 mg/$2,761; 500 µg/$2,256; 5 mg/$5,755; 2 mg/$3,069
GDF9 / GDF-9 Protein
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E. coli
GST
42.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GDF9 / GDF-9 Protein - 12.5% SDS-PAGE of human GDF9 stained with Coomassie Blue
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Wheat Germ Extract
GST
77.8 kDa
2 µg/$439
GDF9 / GDF-9 Protein - Recombinant Growth Differentiation Factor 9 By SDS-PAGE
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E. coli
His
17.0 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
GDF9 / GDF-9 Protein - Recombinant Growth Differentiation Factor 9 By SDS-PAGE
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E. coli
His-T7
19.6 kDa
50 µg/$482; 10 µg/$287; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
GDF9 / GDF-9 Protein
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E. coli
His-T7
19.4 kDa
50 µg/$462; 10 µg/$284; 200 µg/$922; 100 µg/$737; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).