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GDF11 / GDF-11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
Gene Name: | growth differentiation factor 11 |
Family/Subfamily: | TGF beta , not assigned-TGF beta |
Synonyms: | GDF11, BMP11, Bone morphogenetic protein 11, GDF-11, BMP-11 |
Target Sequences: | NM_005811 NP_005802.1 O95390 |
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