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Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Gene Name: | guanylate binding protein 1, interferon-inducible |
Synonyms: | GBP1, GBP-1, GTP-binding protein 1, Guanylate binding protein 1, HuGBP-1 |
Target Sequences: | NM_002053 NP_002044.2 P32455 |
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