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Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.
Gene Name: | Udp-n-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GALNAC-T2) |
Synonyms: | GALNT2, GalNAc-T2, Pp-GaNTase 2, UDP-GalNAc transferase 2 |
Target Sequences: | NM_004481 NP_004472.1 Q10471 |
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