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GALNAC4ST-2 / CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin.
| Gene Name: | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 |
| Synonyms: | CHST9, GalNAc-4-sulfotransferase 2, GalNAc-4-O-sulfotransferase 2, GALNAC4ST-2, GalNAc-4-ST2 |
| Target Sequences: | NM_031422 NP_113610.2 Q7L1S5 |
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