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GAD65

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

GAD65 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Gene Name: glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Synonyms: GAD2, GAD-65, Glutamate decarboxylase 2, GAD65
Target Sequences: NM_000818 NP_000809.1 Q05329

☰ Filters
Products
Proteins (16)
Over-Expression Lysate (4)
Recombinant (12)
GAD65 (16)
No (16)
6His, N-terminus (1)
GST (3)
His, N-Terminal (1)
His/GST,N-terminus (1)
His-GST (1)
His-S (2)
Myc-DDK (Flag) (6)
Human (9)
Mouse (3)
Rat (2)
293T Cells (2)
Baculovirus (2)
E. coli (5)
HEK 293 Cells (4)
Insect Cells (1)
Wheat Germ Extract (2)
Purified (5)
Low endotoxin level (3)
Select
Baculovirus
None
Less than 1.0 EU/µg protein (determined by LAL method).
65.4 kDa
20 µg/$649
GAD65 Protein - Recombinant Glutamate Decarboxylase 2, Acid By SDS-PAGE
Select
E. coli
His-GST
36.1 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
GAD65 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
65.2 kDa
100 µg/$710
GAD65 Protein - Recombinant Glutamate Decarboxylase 2, Acid (GAD2) by SDS-PAGE
Select
E. coli
His, N-Terminal
21.6kDa
10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
GAD65 Protein - 12.5% SDS-PAGE of human GAD2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
91.8 kDa
10 µg/$479; 25 µg/$670
GAD65 Protein - 12.5% SDS-PAGE of human GAD2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
89.9 kDa
10 µg/$479; 25 µg/$670
GAD65 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
65.2 kDa
20 µg/$215
GAD65 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
65.2 kDa
20 µg/$150
GAD65 Protein - Purified recombinant protein GAD2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
65.2 kDa
20 µg/$1,107
GAD65 Protein - Purified recombinant protein GAD2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
65.2 kDa
20 µg/$1,107
GAD65 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
65.2 kDa
100 µg/$494
Select
Insect Cells
His/GST,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
93 kDa
50 µg/$721
Select
E. coli
6His, N-terminus
69.2 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
Baculovirus
GST
Less than 1.0 EU/µg protein (determined by LAL method).
92.6 kDa
100 µg/$982
Select
E. coli
His-S
21.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
GAD65 Protein - Recombinant Glutamate Decarboxylase 2, Acid By SDS-PAGE
Select
E. coli
His-S
21.8 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Viewing 1-16 of 16 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).