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GAD65

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

GAD65 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Gene Name: glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Synonyms: GAD2, GAD-65, Glutamate decarboxylase 2, GAD65
Target Sequences: NM_000818 NP_000809.1 Q05329

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Products
Antibodies (91)
Primary (91)
GAD65 (91)
Human (60)
Mouse (31)
Rat (45)
Bovine (1)
Horse (1)
Monkey (1)
Rabbit (1)
Sheep (1)
IHC (18)
IHC-P (15)
WB (74)
Flo (2)
ELISA (27)
ICC (7)
IF (13)
IP (5)
Peptide-ELISA (1)
RIA (2)
rabbit (66)
mouse (24)
goat (1)
Product Group
IHCPlus (3)
IgG (39)
IgG1 (9)
IgG2a,k (1)
IgG2b,k (5)
monoclonal mc (23)
polyclonal pc (68)
144 (2)
3G3 (1)
5D9G12 (1)
5D9G9 (1)
GAD2/1960 (2)
GAD2/2362 (3)
N-GAD65 (1)
TS106 (1)
APC (4)
APC Conjugated (6)
Azide-free (3)
Biotin Conjugated (9)
BSA-free (2)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (6)
Preservative Free (1)
Ready-to-Use (1)
RPE Conjugated (1)
Unconjugated (43)
aa1-150 (16)
aa109-138 (8)
aa188-374 (8)
aa65-105 (8)
N-Terminus (6)
aa1-585 (4)
Asp572 (1)
aa21-37 (1)
aa4-22 (1)
aa445-473 (1)
aa465-558 (1)
aa515-528 (1)
No (91)
GAD65 Antibody - Anti-GAD2 / GAD65 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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GAD65 Goat anti-Human Polyclonal (aa515-528) Antibody
Mouse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
GAD65 Antibody - GAD65 antibody [C2C3], C-term detects GAD2 protein at cytosol on RT2 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded RT2 xenograft. GAD65 antibody [C2C3], C-term dilution:1:500.
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GAD65 Rabbit anti-Human Polyclonal (aa465-558) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
GAD65 Antibody - GAD2 Antibody western blot of mouse brain tissue lysates (35 ug/lane). The GAD2 antibody detected the GAD2 protein (arrow).
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GAD65 Mouse anti-Human Monoclonal (aa445-473) Antibody
Mouse, Rat, Human
WB
Unconjugated
400 µl/$393
GAD65 Antibody - Immunofluorescence of paraformaldehyde-fixed HeLa, using GAD65 antibody at 1:200 dilution.
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GAD65 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$450
GAD65 Antibody - Anti-GAD65 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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GAD65 Mouse anti-Human Monoclonal (aa4-22) (N-GAD65) Antibody
Human
IHC, IHC-P, IP, RIA, WB
Unconjugated
50 µg/$460
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
GAD65 Antibody - Immunohistochemistry of paraffin-embedded rat brain using GAD2 Antibodyat dilution of 1:100 (40x lens).
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GAD65 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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GAD65 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$331
GAD65 Antibody - GAD65 antibody. IHC(P): Rat Brain Tissue.
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GAD65 Rabbit anti-Human Polyclonal (aa21-37) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Horse, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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GAD65 Mouse anti-Human Monoclonal (5D9G9) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
GAD65 Antibody - Detection limit for recombinant GST tagged GAD2 is 3 ng/ml as a capture antibody.
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GAD65 Mouse anti-Human Monoclonal (3G3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
GAD65 Antibody - GAD2 Antibody western blot of rat brain tissue lysates (35 ug/lane). The GAD2 antibody detected the GAD2 protein (arrow).
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GAD65 Mouse anti-Human Monoclonal (aa109-138) Antibody
Rat, Human
WB
Unconjugated
0.1 ml/$393
GAD65 Antibody - GAD2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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GAD65 Rabbit anti-Human Polyclonal (aa109-138) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
GAD65 Antibody - Western blot of recombinant GAD65.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GAD65 Mouse anti-Rat Monoclonal (aa1-150) Antibody
Rat
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$516; 1 ml/$593; 2 ml/$818; 5 ml/$1,337
GAD65 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
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GAD65 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
GAD65 Antibody - Immunohistochemistry - Anti-GAD65 Picoband antibody
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GAD65 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GAD65 Antibody - IHC of GAD1/2 (D572) pAb in paraffin-embedded human lung carcinoma tissue.
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GAD65 Rabbit anti-Human Polyclonal (Asp572) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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GAD65 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
GAD65 Antibody
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GAD65 Mouse anti-Human Monoclonal (144) Antibody
Mouse, Rat, Human
Flo, IP, RIA, WB
Unconjugated
0.05 mg/$482
GAD65 Antibody - Immunofluorescent analysis of GAD2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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GAD65 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).