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GAD1 / GAD67

glutamate decarboxylase 1 (brain, 67kDa)

GAD1 / GAD67 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Gene Name: glutamate decarboxylase 1 (brain, 67kDa)
Synonyms: GAD1, CPSQ1, GAD-67, Glutamate decarboxylase 1, GAD67, GAD, SCP
Target Sequences: NM_000817 NP_000808.2 Q99259

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Products
Antibodies (95)
Primary (95)
GAD1 / GAD67 (95)
Human (68)
Mouse (55)
Rat (44)
Bat (4)
Bovine (6)
Chimpanzee (3)
Dog (6)
Guinea pig (5)
Hamster (1)
Horse (1)
Monkey (6)
Orangutan (3)
Pig (1)
Rabbit (5)
IHC (38)
IHC-P (18)
WB (88)
ELISA (19)
ICC (3)
IF (5)
IP (6)
Peptide-ELISA (5)
rabbit (67)
mouse (24)
goat (2)
chicken (2)
Product Group
IHCPlus (1)
PathPlus Neuro (2)
IgG (28)
IgG1 (2)
IgG1,k (3)
IgG2a (14)
IgG2b (2)
IgG2b,k (2)
IgM,k (1)
monoclonal mc (24)
polyclonal pc (71)
1D12 (1)
9A6 (1)
GAD1/2391 (2)
GAD1/2563 (2)
OTI3G9 (2)
OTI3H2 (2)
OTI5D8 (2)
APC (3)
APC Conjugated (7)
Azide-free (3)
Biotin Conjugated (8)
BSA-free (2)
Carrier-free (3)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (8)
Magnetic beads Conjugated (1)
PE Conjugated (7)
Sepharose Conjugated (1)
Unconjugated (49)
aa1-97 (24)
N-Terminus (8)
aa514-543 (7)
aa1-200 (2)
440-520 aa, C-terminal (1)
Ala492 (1)
C-Terminus (1)
aa10-24 (1)
aa14-122 (1)
aa471-520 (1)
aa5-216 (1)
aa52-62 (1)
aa526-537 (1)
No (95)
GAD1 / GAD67 Antibody - Anti-GAD67 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
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Neuroscience
GAD1 / GAD67 Goat anti-Human Polyclonal (aa526-537) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
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GAD1 / GAD67 Mouse anti-Rat Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$878
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GAD1 / GAD67 Mouse anti-Rat Monoclonal (APC) Antibody
Mouse, Rat, Human
IHC, WB
APC Conjugated
100 µl/$1,094
GAD1 / GAD67 Antibody - Immunofluorescent staining of GAD67 antibody. A tissue section through an adult mouse brain showing GAD-1 (red staining) in basket cells of the hippocampal formation. Green staining is autofluorescence from green fluorescent protein (GFP) expressed in this transgenic mouse. Picture courtesy of Dr. Felix Eckenstein, University of Vermont.
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GAD1 / GAD67 Chicken anti-Human Polyclonal Antibody
Mouse, Human
ICC, IHC, WB
Unconjugated
1 ml/$1,050
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GAD1 / GAD67 Chicken anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC
Unconjugated
1000 µl/$666
GAD1 / GAD67 Antibody - Anti-Mouse Gad67 staining (10 µg/ml) of a mouse brain formalin-fixed, paraffin-embedded tissue section; seen at 20x (left) and 40x (right) magnification. Staining of neural cells of the brain cortex is observed.
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GAD1 / GAD67 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
100 µg/$491
GAD1 / GAD67 Antibody
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GAD1 / GAD67 Mouse anti-Mouse Monoclonal (9A6) Antibody
Mouse, Rat
IHC, WB
Unconjugated
100 µg/$447
GAD1 / GAD67 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal (N-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
GAD1 / GAD67 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
GAD1 / GAD67 Antibody - Anti-GAD67 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Neuroscience
GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa471-520) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
GAD1 / GAD67 Antibody - Immunofluorescence of paraformaldehyde-fixed HeLa using GAD67 antibody at 1:200 dilution.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa5-216) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
GAD1 / GAD67 Antibody - IHC of paraffin-embedded breast tissue using anti-GAD1 mouse monoclonal antibody. (Dilution 1:50).
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GAD1 / GAD67 Mouse anti-Human Monoclonal (OTI5D8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
GAD1 / GAD67 Antibody - Immunohistochemical staining of paraffin-embedded breast tissue using anti-GAD1 mouse monoclonal antibody. (Dilution 1:50).
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GAD1 / GAD67 Mouse anti-Human Monoclonal (OTI3H2) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
GAD1 / GAD67 Antibody - Immunohistochemical staining of paraffin-embedded breast tissue using anti-GAD1 mouse monoclonal antibody. (Dilution 1:50).
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GAD1 / GAD67 Mouse anti-Human Monoclonal (Carrier-free) (OTI3H2) Antibody
Dog, Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
GAD1 / GAD67 Antibody - GAD1 / GAD67 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
GAD1 / GAD67 Antibody - Western blot analysis of extracts of various cell lines.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
GAD1 / GAD67 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GAD1 / GAD67 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GAD1 / GAD67 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa1-200) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GAD1 / GAD67 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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GAD1 / GAD67 Rabbit anti-Human Polyclonal (aa1-200) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GAD1 / GAD67 Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-GAD1 mouse monoclonal antibody. (Dilution 1:50).
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GAD1 / GAD67 Mouse anti-Human Monoclonal (OTI3G9) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
GAD1 / GAD67 Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-GAD1 mouse monoclonal antibody. (Dilution 1:50).
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GAD1 / GAD67 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G9) Antibody
Human, Monkey
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
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GAD1 / GAD67 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µg/$564
GAD1 / GAD67 Antibody - IHC testing of FFPE human brain with GAD67 antibody (clone GAD1/2391). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
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GAD1 / GAD67 Mouse anti-Human Monoclonal (GAD1/2391) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
GAD1 / GAD67 Antibody - IHC testing of FFPE human brain with GAD67 antibody (clone GAD1/2391). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
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GAD1 / GAD67 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (GAD1/2391) Antibody
Human
ELISA, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).