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GAA / Alpha-Glucosidase, Acid

glucosidase, alpha; acid

GAA / Alpha-Glucosidase, Acid is acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.

Gene Name: glucosidase, alpha; acid
Synonyms: GAA, Acid maltase, Aglucosidase alfa, Glucosidase, alpha, Lysosomal alpha-glucosidase, Glucosidase, alpha acid, LYAG
Target Sequences: NM_000152 NP_000143.2 P10253

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Proteins (17)
Over-Expression Lysate (6)
Recombinant (11)
GAA / Alpha-Glucosidase, Acid (17)
No (17)
GST (1)
GST, N-terminus (1)
His (2)
His, N-terminus (1)
His-T7 (3)
Myc-DDK (Flag) (9)
Human (10)
Mouse (2)
Rat (2)
293T Cells (3)
E. coli (6)
HEK 293 Cells (6)
Wheat Germ Extract (2)
Purified (1)
GAA / Alpha-Glucosidase, Acid Protein - Recombinant Glucosidase Alpha, Acid By SDS-PAGE
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E. coli
His
21.2 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
GAA / Alpha-Glucosidase, Acid Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GAA / Alpha-Glucosidase, Acid Protein - Recombinant Glucosidase Alpha, Acid By SDS-PAGE
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E. coli
His
18.5 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
GAA / Alpha-Glucosidase, Acid Protein - Recombinant Glucosidase Alpha, Acid By SDS-PAGE
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E. coli
His, N-terminus
22.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
GAA / Alpha-Glucosidase, Acid Protein - Purified recombinant protein GAA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
102.5 kDa
20 µg/$1,107
GAA / Alpha-Glucosidase, Acid Protein - Purified recombinant protein GAA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
102.5 kDa
20 µg/$1,107
GAA / Alpha-Glucosidase, Acid Protein - Purified recombinant protein GAA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
102.5 kDa
20 µg/$1,107
GAA / Alpha-Glucosidase, Acid Protein - Recombinant Glucosidase Alpha, Acid By SDS-PAGE
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E. coli
His-T7
22.3 kDa
10 µg/$285; 50 µg/$465; 100 µg/$742; 200 µg/$930; 1 mg/$2,052; 500 µg/$1,586; 5 mg/$3,249; 2 mg/$2,241
GAA / Alpha-Glucosidase, Acid Protein - Recombinant  Glucosidase Alpha, Acid By SDS-PAGE
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E. coli
His-T7
23.5 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
GAA / Alpha-Glucosidase, Acid Protein - Recombinant  Glucosidase Alpha, Acid By SDS-PAGE
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E. coli
His-T7
21.3 kDa
10 µg/$285; 50 µg/$465; 100 µg/$742; 200 µg/$930; 1 mg/$2,052; 500 µg/$1,586; 5 mg/$3,249; 2 mg/$2,241
GAA / Alpha-Glucosidase, Acid Protein - 12.5% SDS-PAGE of human GAA stained with Coomassie Blue
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Wheat Germ Extract
GST
131.7 kDa
10 µg/$479; 25 µg/$670
GAA / Alpha-Glucosidase, Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
105.32 kDa
20 µg/$150
GAA / Alpha-Glucosidase, Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
105.32 kDa
20 µg/$215
GAA / Alpha-Glucosidase, Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
105.32 kDa
20 µg/$150
GAA / Alpha-Glucosidase, Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
105.32 kDa
100 µg/$494
GAA / Alpha-Glucosidase, Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
105.32 kDa
100 µg/$710
GAA / Alpha-Glucosidase, Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
105.32 kDa
100 µg/$494
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).