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FXYD3 belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Name: | FXYD domain containing ion transport regulator 3 |
Family/Subfamily: | Ion Channel Regulator , not assigned-Ion Channel Regulator |
Synonyms: | FXYD3, Phospholemman-like protein, Mammary tumor 8 kDa protein, Phospholemman-like, PLML, MAT-8, MAT8 |
Target Sequences: | NM_005971 NP_005962.1 Q14802 |
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