FXN / Frataxin

frataxin

Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.

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Products

Antibodies (93)

Proteins (18)

ELISA Kits (6)

Type

Custom (2)

Over-Expression Lysate (4)

Primary (93)

Recombinant (14)

Sandwich (4)

Target

FXN / Frataxin (117)

Reactivity

Human (83)

Mouse (32)

Rat (13)

Bat (3)

Bovine (7)

Dog (3)

Gibbon (6)

Guinea pig (3)

Horse (6)

Monkey (6)

Pig (3)

Rabbit (6)

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Application

IHC (27)

IHC-P (14)

WB (86)

Flo (5)

ELISA (28)

ICC (3)

IF (20)

IP (2)

Peptide-ELISA (1)

Host

rabbit (66)

mouse (26)

rabbit-new zealand white (1)

Product Group

IHCPlus (3)

Isotype

IgG (38)

IgG1 (16)

IgG1,k (3)

IgG2b,k (6)

Clonality

monoclonal mc (25)

polyclonal pc (68)

Clone

1D9 (1)

AT10E11 (1)

FDAX-1 (3)

FXN/2124 (3)

OTI1C12 (2)

OTI1F2 (2)

OTI3B6 (2)

OTI3C3 (2)

OTI3C7 (2)

OTI3F3 (2)

OTI4D7 (2)

OTI4G4 (2)

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Format

96-Well Microplate (1)

96-Well Strip Plate (5)

APC (2)

APC Conjugated (6)

Azide-free (5)

Biotin Conjugated (9)

BSA-free (2)

Carrier-free (8)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (9)

HRP Conjugated (9)

PE Conjugated (6)

Ready-to-Use (2)

Unconjugated (50)

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Epitope

aa41-207 (8)

aa57-198 (8)

aa143-172 (7)

aa36-64 (7)

aa72-102 (7)

aa105-154 (4)

aa80-129 (4)

C-Terminus (2)

Publications

No (114)

Yes (3)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

10His, N-terminus (1)

10His, N-terminus + Myc, C-terminus (1)

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, N-terminus (4)

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Cynomolgus monkey (1)

Human (10)

Mouse (4)

Rat (2)

Source

293T Cells (2)

E. coli (10)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (7)

Select

FXN / Frataxin Antibody (aa105-154) LS-B5892

Antibody:

FXN / Frataxin Rabbit anti-Rat Polyclonal (aa105-154) Antibody

Reactivity:

Rat

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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FXN / Frataxin Antibody (aa105-154, Biotin) LS-C454563

Antibody:

FXN / Frataxin Rabbit anti-Rat Polyclonal (aa105-154) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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FXN / Frataxin Antibody (aa57-198) LS-B15909

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal (aa57-198) Antibody

Reactivity:

Human

Applications:

ICC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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FXN / Frataxin Antibody (clone 1D9) LS-C197243

(4.2) Rating

(3) Publication(s)

Antibody:

FXN / Frataxin Mouse anti-Human Monoclonal (1D9) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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FXN / Frataxin Antibody (clone AT10E11) LS-C755462

Antibody:

FXN / Frataxin Mouse anti-Human Monoclonal (AT10E11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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FXN / Frataxin Antibody (aa143-172) LS-C327400

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal (aa143-172) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

FXN / Frataxin Antibody (aa143-172, Azide-free, HRP) LS-C219381

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal (aa143-172) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• HRP, Azide-free

• Unconjugated
• HRP, Azide-free

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Human FXN / Frataxin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68166

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.8 kDa

Price:

20 µg/$1,107

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Cynomolgus monkey FXN / Frataxin Protein (Recombinant 6His, N-terminus) (aa81-210) - LS-G21788

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

18.3 kD

Price:

100 µg/$598; 20 µg/$405; 1 mg/$1,679

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Human FXN / Frataxin (Sandwich ELISA) ELISA Kit - LS-F23370

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

23.44 - 1500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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FXN / Frataxin Antibody (clone OTI1C12) LS-C173723

Antibody:

FXN / Frataxin Mouse anti-Human Monoclonal (OTI1C12) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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Human FXN / Frataxin Protein (Recombinant His) - LS-G669

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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FXN / Frataxin Antibody (C-Terminus) LS-C6891

Antibody:

FXN / Frataxin Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$513; 100 µg/$832

Select

IHC-plus™ FXN / Frataxin Antibody LS-B14580

(4.0) Rating

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

FXN / Frataxin Antibody (HRP) LS-C375745

Antibody:

FXN / Frataxin Rabbit anti-Mouse Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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FXN / Frataxin (Sandwich ELISA) ELISA Kit - LS-F66885

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

FXN / Frataxin Antibody (aa72-102, Azide-free, HRP) LS-C219375

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal (aa72-102) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

FXN / Frataxin Antibody (aa72-102, APC) LS-C219372

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal (aa72-102) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• HRP, Azide-free
• APC

• HRP, Azide-free
• APC

Select

FXN / Frataxin Antibody LS-C331670

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

Mouse FXN / Frataxin Protein (Recombinant 6His, N-terminus) (aa78-207) - LS-G22926

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

16.4 kD

Price:

1 mg/$1,683; 100 µg/$499; 20 µg/$364

Select

Mouse FXN / Frataxin Protein (Recombinant 6His, N-terminus) (aa41-207) - LS-G14956

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

22.4 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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FXN / Frataxin Antibody (clone OTI4G4) LS-C337644

Antibody:

FXN / Frataxin Mouse anti-Human Monoclonal (OTI4G4) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FXN / Frataxin Antibody (clone OTI3C3) LS-C173775

Antibody:

FXN / Frataxin Mouse anti-Human Monoclonal (OTI3C3) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FXN / Frataxin Antibody (clone OTI3B6) LS-C173765

Antibody:

FXN / Frataxin Mouse anti-Human Monoclonal (OTI3B6) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FXN / Frataxin Antibody LS-C806234

Antibody:

FXN / Frataxin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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