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FVT1 / KDSR

3-ketodihydrosphingosine reductase

FVT1 / KDSR catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.

Gene Name: 3-ketodihydrosphingosine reductase
Synonyms: KDSR, 3-dehydrosphinganine reductase, DHSR, FVT-1, FVT1, KDS reductase, SDR35C1
Target Sequences: NM_002035 NP_002026.1 Q06136

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
FVT1 / KDSR (8)
No (8)
GST (2)
His (1)
His, N-Terminal (1)
His-GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
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293T Cells
Myc-DDK (Flag)
36.19 kDa
20 µg/$150
FVT1 / KDSR Protein - Recombinant Follicular Lymphoma Variant Translocation 1 (FVT1) by SDS-PAGE
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E. coli
His, N-Terminal
26.6kDa
10 µg/$269; 50 µg/$367; 200 µg/$732; 100 µg/$587; 1 mg/$1,773; 500 µg/$1,340; 5 mg/$2,729; 2 mg/$1,952
FVT1 / KDSR Protein - 12.5% SDS-PAGE of human FVT1 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.05 kDa
10 µg/$479; 25 µg/$670
FVT1 / KDSR Protein - 12.5% SDS-PAGE of human FVT1 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.15 kDa
10 µg/$479; 25 µg/$670
FVT1 / KDSR Protein - Purified recombinant protein KDSR was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
33.4 kDa
20 µg/$1,107
FVT1 / KDSR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
36.19 kDa
100 µg/$494
FVT1 / KDSR Protein - Recombinant Follicular Lymphoma Variant Translocation 1 (FVT1) by SDS-PAGE
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E. coli
His-GST, N-terminus
56.7kDa
10 µg/$231; 50 µg/$263; 200 µg/$315; 100 µg/$294; 1 mg/$782; 500 µg/$522; 5 mg/$1,496; 2 mg/$912
FVT1 / KDSR Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-8 of 8 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).