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FUT8 is an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.
Gene Name: | Fucosyltransferase 8 (alpha (1,6) Fucosyltransferase) |
Synonyms: | FUT8, Alpha1-6FucT, Fucosyltransferase 8, Alpha-(1,6)-fucosyltransferase |
Target Sequences: | NM_004480 NP_004471.4 Q9BYC5 |
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