FURIN

furin (paired basic amino acid cleaving enzyme)

FURIN is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140 and may play a role in tumor progression. This gene is located in close proximity to family member proprotein convertase subtilisin/kexin type 6 and upstream of the FES oncogene. Alternative splicing results in multiple transcript variants.

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Products

ELISA Kits (12)

Type

Custom (2)

Sandwich (10)

Target

FURIN (12)

Reactivity

Human (7)

Mouse (2)

Rat (2)

Bovine (1)

Product Group

Coronavirus Detection (12)

ELISA Kits for Associated Targets (12)

Format

96-Well Microplate (3)

96-Well Strip Plate (9)

Publications

No (12)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Plasma (6)

Serum (6)

Tissue Homogenates (6)

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Mouse FURIN (Sandwich ELISA) ELISA Kit - LS-F32096

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat FURIN (Sandwich ELISA) ELISA Kit - LS-F9935

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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Human FURIN (Sandwich ELISA) ELISA Kit - LS-F92

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

13.71 - 3333 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$760

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Human FURIN (Sandwich ELISA) ELISA Kit - LS-F2755

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

312 - 20000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$699

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Human FURIN (Sandwich ELISA) ELISA Kit - LS-F7234

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$730

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Rat FURIN (Custom) ELISA Kit - LS-F65974

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$669

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Human FURIN (Sandwich ELISA) ELISA Kit - LS-F66635

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse FURIN (Sandwich ELISA) ELISA Kit - LS-F66758

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Bovine FURIN (Custom) ELISA Kit - LS-F66448

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$669

Select

Human FURIN (Sandwich ELISA) ELISA Kit - LS-F21159

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human FURIN (Sandwich ELISA) ELISA Kit - LS-F36894

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human FURIN (Sandwich ELISA) ELISA Kit - LS-F24510

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

312 - 20000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$624

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