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FUCA2 is a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells.
Gene Name: | fucosidase, alpha-L- 2, plasma |
Synonyms: | FUCA2, Alpha-L-fucosidase 2, DJ20N2.5, Fucosidase, alpha-L- 2, plasma, Plasma alpha-L-fucosidase, RP1-20N2.5 |
Target Sequences: | NM_032020 NP_114409.2 Q9BTY2 |
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