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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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FRMPD2
FERM and PDZ domain containing 2
FRMPD2 is a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants.
| Gene Name: | FERM and PDZ domain containing 2 |
| Synonyms: | FRMPD2, PDZ domain containing 5C, PDZD5C, PDZK4, PDZK5C |
| Target Sequences: | AX285248 NP_001018081.3 Q68DX3 |
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