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The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene.
Gene Name: | FOS-like antigen 1 |
Synonyms: | FOSL1, FOS-like antigen 1, Fos-related antigen 1, FRA, FOS-like antigen-1, FRA1, Fra-1 |
Target Sequences: | NM_005438 NP_005429.1 P15407 |
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