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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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FPR1 / FPR
formyl peptide receptor 1
Formyl peptide receptor 1, a Chemoattractant Receptor, mediates chemotaxis, degranulation, and superoxide production, as part of the inflammatory response. Bacterial N-formylmethionyl peptides and Annexin A1, specific ligands for FPR1, attract polymorphonuclear neutrophils to sites of infection. FPR receptors promote the phosphorylation and downregulation of CCR5, which has been shown to inhibit HIV infection. Therefore, ligands for an FPR receptor may be able to inhibit HIV infection. (WO0157074)
| Gene Name: | formyl peptide receptor 1 |
| Family/Subfamily: | GPCR , Chemoattractant |
| Synonyms: | FPR1, FPR-1, FMet-Leu-Phe receptor, FMLP, Formyl peptide receptor 1, FPR, N-formyl peptide receptor, FMLP receptor, Fpr receptor, N-formyl peptide receptor 1 |
| Target Sequences: | NM_002029 NP_002020.1 P21462 |
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