Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
Gene Name: | prostaglandin F receptor (FP) |
Family/Subfamily: | GPCR , Prostanoid |
Synonyms: | PTGFR, PGF receptor, PGF2-alpha receptor, Prostaglandin F receptor (FP), FP, PGF2 alpha receptor, Prostaglandin F receptor, Prostanoid FP receptor |
Target Sequences: | NM_000959 NP_000950.1 P43088 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.