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FOXP3
forkhead box P3
FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Gene Name: | forkhead box P3 |
| Synonyms: | FOXP3, AIID, DIETER, Forkhead box protein P3, JM2, Forkhead box P3, FOXP3delta7, XPID, PIDX, SCURFIN |
| Target Sequences: | NM_014009 NP_054728.2 Q9BZS1 |
Publications (5)
1
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells. Ochando JC, Yopp AC, Yang Y, Garin A, Li Y, Boros P, Llodra J, Ding Y, Lira SA, Krieger NR, Bromberg JS. Journal of immunology (Baltimore, Md. : 1950). 2005 174:6993-7005. (IHC)
[PubMed:15905542]
2
Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells. Lim HW, Hillsamer P, Banham AH, Kim CH. Journal of immunology (Baltimore, Md. : 1950). 2005 175:4180-3.
[PubMed:16177055]
3
Compartmentalization of immune responses in human tuberculosis: few CD8+ effector T cells but elevated levels of FoxP3+ regulatory t cells in the granulomatous lesions. Rahman S, Gudetta B, Fink J, Granath A, Ashenafi S, Aseffa A, Derbew M, Svensson M, Andersson J, Brighenti SG. The American journal of pathology. 2009 174:2211-24.
[PubMed:19435796]
[PMC:PMC2684186]
☰ Filters
Products
Proteins
(12)
Type
Over-Expression Cell Culture Supernatant
(1)
Over-Expression Lysate
(4)
Recombinant
(7)
Target
FOXP3
(12)
Publications
No
(12)
Tag
6His, N-terminus
(1)
GST
(1)
His
(1)
His, N-Terminal
(2)
His-GST
(1)
His-T7
(1)
Myc-DDK (Flag)
(5)
Species
Human
(9)
Mouse
(1)
Source
293T Cells
(2)
E. coli
(5)
HEK 293 Cells
(4)
Wheat Germ Extract
(1)
Purification
Purified
(2)
Low Endotoxin Level
Low endotoxin level
(1)
E. coli
His-GST
57.6 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
HEK 293 Cells
Myc-DDK (Flag)
47.1 kDa
20 µg/$1,107
E. coli
His, N-Terminal
43.2 kDa
50 µg/$419
E. coli
His-T7
29.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Wheat Germ Extract
GST
73.6 kDa
2 µg/$439
E. coli
His, N-Terminal
46 kDa
10 µg/$265; 200 µg/$484; 50 µg/$315
293T Cells
Myc-DDK (Flag)
47.1 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
43.2 kDa
20 µg/$150
HEK 293 Cells
6His, N-terminus
46 kDa
200 µl/$283
HEK 293 Cells
Myc-DDK (Flag)
47.1 kDa
100 µg/$710
HEK 293 Cells
Myc-DDK (Flag)
43.2 kDa
100 µg/$494
E. coli
62 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
6.93 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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