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FOXO4 / AFX1

forkhead box O4

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

Gene Name: forkhead box O4
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXO4, AFX, AFX1, Forkhead box O4, Forkhead box protein O4, MLLT7
Target Sequences: NM_005938 NP_005929.2 P98177

☰ Filters
Products
Antibodies (81)
Primary (81)
FOXO4 / AFX1 (81)
Human (79)
Mouse (43)
Rat (16)
Bat (3)
Bovine (7)
Chimpanzee (3)
Dog (8)
Gibbon (6)
Guinea pig (3)
Hamster (6)
Horse (8)
Monkey (10)
Pig (9)
Rabbit (8)
Sheep (3)
IHC (35)
IHC-P (9)
WB (73)
ELISA (27)
ICC (4)
IF (15)
Peptide-ELISA (12)
rabbit (66)
mouse (14)
goat (1)
Product Group
IHCPlus (3)
IgG (39)
IgG1 (10)
IgG2a (4)
monoclonal mc (14)
polyclonal pc (67)
OTI10F12 (2)
OTI10G3 (2)
OTI1A4 (2)
OTI2C5 (2)
OTI5A5 (2)
OTI8A8 (2)
OTI8F1 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (7)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (67)
aa206-505 (14)
C-Terminus (8)
pSer197 (8)
N-Terminus (6)
pThr451 (6)
aa108-157 (4)
140-220 aa (2)
390-470 aa (2)
pSer193 (2)
pSer262 (2)
200-280 aa (1)
Internal (1)
Lys447 (1)
Pro191 (1)
aa206-240 (1)
aa228-277 (1)
aa415-450 (1)
aa417-466 (1)
aa455-505 (1)
aa459-471 (1)
aa59-73 (1)
p197 (1)
p451 (1)
No (81)
FOXO4 / AFX1 Antibody - Anti-FOXO4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXO4 / AFX1 Antibody - FOXO4 antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (aa108-157) Antibody
Human
WB
Unconjugated
100 µl/$424
FOXO4 / AFX1 Antibody - Anti-FOXO4 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
FOXO4 / AFX1 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using AFX (Phospho-Ser197) Antibody. The picture on the right is blocked with the phospho peptide.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (pSer197) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
FOXO4 / AFX1 Antibody - Immunohistochemical analysis of FOXO4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
FOXO4 / AFX1 Antibody - Immunohistochemical analysis of FOXO4 (pS197) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (pSer197) Antibody
Mouse, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
FOXO4 / AFX1 Antibody - 1:200 staining mouse liver tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (pSer197) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FOXO4 / AFX1 Antibody - 1:200 staining mouse lung tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (pThr451) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FOXO4 / AFX1 Antibody - 1:100 staining mouse pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FOXO4 / AFX1 Antibody - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (pSer197) Antibody
IF, IHC, WB
Unconjugated
20 µl/$287; 100 µl/$431
FOXO4 / AFX1 Antibody - Anti-FOXO4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (aa59-73) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
FOXO4 / AFX1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-FOXO4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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FOXO4 / AFX1 Mouse anti-Human Monoclonal (aa206-505) (OTI1A4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
FOXO4 / AFX1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-FOXO4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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FOXO4 / AFX1 Mouse anti-Human Monoclonal (aa206-505) (Carrier-free) (OTI1A4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FOXO4 / AFX1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FOXO4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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FOXO4 / AFX1 Mouse anti-Human Monoclonal (aa206-505) (OTI8A8) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
FOXO4 / AFX1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FOXO4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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FOXO4 / AFX1 Mouse anti-Human Monoclonal (aa206-505) (Carrier-free) (OTI8A8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FOXO4 / AFX1 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using FOXO4 (Phospho-Ser262) Antibody. The picture on the right is blocked with the phospho peptide.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal (pSer262) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
FOXO4 / AFX1 Antibody - Western blot of FOXO4 expression in K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
FOXO4 / AFX1 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FOXO4 / AFX1 Antibody - Western blot of FoxO4 antibody
Select
FOXO4 / AFX1 Rabbit anti-Human Polyclonal (390-470 aa) Antibody
Mouse, Human, Monkey
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
FOXO4 / AFX1 Rabbit anti-Human Polyclonal (200-280 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
FOXO4 / AFX1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
FOXO4 / AFX1 Antibody - Western blot of FoxO4 antibody
Select
FOXO4 / AFX1 Rabbit anti-Human Polyclonal (140-220 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
FOXO4 / AFX1 Antibody - Western blot of Phospho-FoxO4 (S197) antibody
Select
FOXO4 / AFX1 Rabbit anti-Human Polyclonal (140-220 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).