Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Gene Name: | forkhead box O4 |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | FOXO4, AFX, AFX1, Forkhead box O4, Forkhead box protein O4, MLLT7 |
Target Sequences: | NM_005938 NP_005929.2 P98177 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.