Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Gene Name: | forkhead box L2 |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | FOXL2, BPES, BPES1, Forkhead box L2, Forkhead box protein L2, PFRK, PINTO, POF3 |
Target Sequences: | NM_023067 NP_075555.1 P58012 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.