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FOXL2

forkhead box L2

Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Gene Name: forkhead box L2
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXL2, BPES, BPES1, Forkhead box L2, Forkhead box protein L2, PFRK, PINTO, POF3
Target Sequences: NM_023067 NP_075555.1 P58012

Publications (2)

1
A Human Gonadal Cell Model From Induced Pluripotent Stem Cells. Rodríguez Gutiérrez D, Eid W, Biason-Lauber A. Frontiers in genetics. 2018 October;9:498. [Full Text Article] [PubMed:30405703] [PMC:PMC6207579] Related Antibodies: LS-B12865.
2
SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and Maturation. Muhammad Idrees, Vikas Kumar, Myeong-Don Joo, Niaz Ali, Keun-Woo Lee, Il-Keun Kong. Frontiers in cell and developmental biology. 2021 Jan;8:611503. [Full Text Article] [PubMed:33553147] [PMC:PMC7862566] Related Antibodies: LS-B12865.

☰ Filters
Antibodies (38)
Proteins (4)
Over-Expression Lysate (2)
Primary (38)
Recombinant (2)
FOXL2 (42)
Human (36)
Mouse (17)
Rat (13)
Bovine (11)
Chimpanzee (6)
Dog (6)
Goat (6)
Monkey (7)
Pig (11)
Rabbit (8)
Zebrafish (3)
IHC (1)
IHC-P (1)
WB (32)
Flo (7)
DB (1)
ELISA (12)
IP (2)
Peptide-ELISA (2)
rabbit (35)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (23)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (36)
262C1a (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
Magnetic beads Conjugated (1)
PE Conjugated (1)
Sepharose Conjugated (1)
Unconjugated (19)
N-Terminus (8)
aa3-29 (7)
C-Terminus (4)
aa154-203 (4)
pSer263 (2)
200-280 aa (1)
aa314-376 (1)
aa364-376 (1)
No (41)
Yes (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
FOXL2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
FOXL2 Goat anti-Human Polyclonal (aa364-376) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Select
FOXL2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$564
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
FOXL2 Antibody - FOXL2 Antibody western blot of HeLa cell line lysates (35 ug/lane). The FOXL2 antibody detected the FOXL2 protein (arrow).
Select
FOXL2 Rabbit anti-Human Polyclonal (aa3-29) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
Select
FOXL2 Rabbit anti-Human Polyclonal (200-280 aa) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
FOXL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
FOXL2 Antibody - Western blot analysis of Mouse brain and heart tissue, using FOXL2 Polyclonal Antibody at dilution of 1:750.
Select
FOXL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FOXL2 Antibody - Positive Western Blot detected in A549 whole cell lysate. All lanes: FOXL2 antibody at 3.7 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 39 KDa. Observed band size: 49 KDa
Select
FOXL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
FOXL2 Antibody - Western blot analysis of extracts from K562 cells, treated with Na3VO4 (0.3nM, 40mins), using FOXL2 (Phospho-Ser263) antibody.
Select
FOXL2 Rabbit anti-Human Polyclonal (pSer263) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
FOXL2 Antibody - Western blot analysis of immunized recombinant protein, using anti-FOXL2 monoclonal antibody.
Select
FOXL2 Mouse anti-Human Monoclonal (262C1a) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
FOXL2 Antibody - Western blot analysis of lysates from K562 cells treated with Na3VO4 0.3mM 40', using FOXL2 (Phospho-Ser263) Antibody. The lane on the right is blocked with the phospho peptide.
Select
FOXL2 Rabbit anti-Human Polyclonal (pSer263) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
FOXL2 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$786
Select
FOXL2 Rabbit anti-Human Polyclonal (aa314-376) Antibody
Rabbit, Mouse, Bovine, Pig, Human
ELISA
Unconjugated
100 µl/$450
Select
FOXL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$357
Select
FOXL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$357
FOXL2 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FOXL2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
FOXL2 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FOXL2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Pig, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$442
FOXL2 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FOXL2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Pig, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$442
FOXL2 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FOXL2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Pig, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$442
FOXL2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FOXL2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$380
Viewing 1-25 of 42 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).