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This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.
Gene Name: | forkhead box E3 |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | FOXE3, ASMD, FKHL12, Forkhead box E3, Forkhead box protein E3, Forkhead protein 8, FREAC-8, FREAC8 |
Target Sequences: | NM_012186 NP_036318.1 Q13461 |
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