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FOXA1

forkhead box A1

Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate; FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription; required for ESR1 binding to the NKX2-1 promoter in breast cancer cells; binds to the RPRM promter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.

Gene Name: forkhead box A1
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXA1, Forkhead box A1, Forkhead box protein A1, HNF-3-alpha, HNF-3A, TCF-3A, TCF3A, HNF3A, Transcription factor 3A
Target Sequences: NM_004496 NP_004487.2 P55317

☰ Filters
Antibodies (76)
Proteins (7)
Over-Expression Lysate (2)
Primary (76)
Recombinant (5)
FOXA1 (83)
Human (74)
Mouse (21)
Rat (11)
Bat (4)
Bovine (7)
Dog (10)
Guinea pig (3)
Hamster (1)
Monkey (7)
Pig (7)
Xenopus (1)
Zebrafish (7)
IHC (18)
IHC-P (30)
WB (59)
Flo (12)
ChrIP (1)
ELISA (16)
ICC (9)
IF (20)
IP (1)
Peptide-ELISA (2)
RNAi (1)
rabbit (45)
mouse (30)
goat (1)
Product Group
IHCPlus (5)
PathPlus Cancer (3)
PathPlus Cancer Pathology (3)
IgG (28)
IgG1 (4)
IgG1,k (11)
IgG2a,k (6)
IgG2b (4)
IgG2b,k (5)
monoclonal mc (28)
polyclonal pc (44)
recombinant monoclonal rmc (4)
1B1 (1)
2D7 (1)
3C1 (1)
4F6 (1)
FOXA1/1241 (2)
FOXA1/1512 (2)
FOXA1/1514 (2)
FOXA1/1515 (2)
FOXA1/1518 (2)
FOXA1/1519 (2)
FOXA1/2230R (2)
OTI3A8 (2)
OTI3C1 (2)
rFOXA1/1515 (2)
TS106 (1)
APC (1)
APC Conjugated (3)
Azide-free (9)
Biotin Conjugated (7)
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Carrier-free (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
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PE Conjugated (3)
Preservative Free (1)
Unconjugated (47)
N-Terminus (8)
aa15-233 (8)
aa270-298 (7)
aa372-472 (4)
aa395-444 (4)
C-Terminus (1)
aa1-473 (1)
aa143-171 (1)
aa253-472 (1)
aa422-472 (1)
aa429-439 (1)
aa7-86 (1)
No (83)
GST, N-terminus (3)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (1)
FOXA1 Antibody - Anti-FOXA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Cancer Pathology
Cancer
FOXA1 Mouse anti-Human Monoclonal (3C1) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$485
FOXA1 Antibody - Anti-FOXA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FOXA1 Rabbit anti-Human Polyclonal (aa395-444) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
FOXA1 Antibody - Anti-FOXA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FOXA1 Rabbit anti-Human Polyclonal (aa395-444) (FITC) Antibody
Zebrafish, Pig, Rat, Mouse, Dog, Guinea pig, Bovine, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
FOXA1 Antibody - Anti-FOXA1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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FOXA1 Goat anti-Human Polyclonal (aa429-439) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Bovine, Bat, Human, Monkey
ChrIP, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1512). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
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FOXA1 Mouse anti-Human Monoclonal (FOXA1/1512) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1512). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
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FOXA1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (FOXA1/1512) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
FOXA1 Antibody - Anti-FOXA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer Pathology
Cancer
FOXA1 Mouse anti-Human Monoclonal (2D7) Antibody
Human
ELISA, IHC, IHC-P, RNAi, WB
Unconjugated
100 µg/$485
FOXA1 Antibody - Anti-FOXA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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FOXA1 Mouse anti-Human Monoclonal (4F6) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXA1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FOXA1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
FOXA1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FOXA1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Zebrafish, Rat, Mouse, Human
WB
Biotin Conjugated
100 µl/$469
FOXA1 Antibody - Immunochemical staining of mouse FOXA1 in mouse prostate with rabbit polyclonal antibody at 1:1500 dilution, formalin-fixed paraffin embedded sections.
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FOXA1 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ICC, IF, IHC-P, WB
Unconjugated, Preservative Free
100 µl/$412
FOXA1 Antibody - Anti-FOXA1 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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FOXA1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXA1 Antibody - Immunofluorescence of monoclonal antibody to FOXA1 on HepG2 cell. [antibody concentration 10 ug/ml]
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FOXA1 Mouse anti-Human Monoclonal (1B1) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$423
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1241). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9 for 10-20 min followed by cooling at RT for 20 min.
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FOXA1 Mouse anti-Human Monoclonal (FOXA1/1241) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1241). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9 for 10-20 min followed by cooling at RT for 20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (FOXA1/1241) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
FOXA1 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FOXA1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1514). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (FOXA1/1514) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1514). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (FOXA1/1514) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
FOXA1 Antibody - Western blot of FOXA1 antibody.
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FOXA1 Rabbit anti-Human Polyclonal (aa15-233) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Select
FOXA1 Mouse anti-Human Monoclonal (aa7-86) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$832
Select
FOXA1 Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Human
ICC, IHC, WB
Biotin Conjugated
100 µl/$1,054
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1518). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (FOXA1/1518) Antibody
Human
Flo, IF, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1518). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (FOXA1/1518) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1515). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (FOXA1/1515) Antibody
Human
Flo, IF, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
FOXA1 Antibody - IHC testing of FFPE human prostate carcinoma with FOXA1 antibody (clone FOXA1/1515). HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.
Select
FOXA1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (FOXA1/1515) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
Viewing 1-25 of 83 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).