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FOSB

FBJ murine osteosarcoma viral oncogene homolog B

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: FBJ murine osteosarcoma viral oncogene homolog B
Synonyms: FOSB, Activator protein 1, AP-1, GOS3, G0s3, GOSB, Protein fosB
Target Sequences: NM_006732 NP_006723.2 P53539

Publications (1)

1
FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics. Watanabe H, Henriksson R, Ohnishi YN, Ohnishi YH, Harper C, Sheedy D, Garrick T, Nyberg F, Nestler EJ, Bakalkin G, Yakovleva T. Addiction biology. 2009 14:294-7. (WB; Human) [Full Text Article] [PubMed:19523044] [PMC:PMC2828493]

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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).